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Apexbio Technology LLC H-9 dihydrochloride 116700-36-8 50mg
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Supplier:  Apexbio Technology LLC B500150

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H-9 dihydrochloride (CAS 116700-36-8) is a cell-permeable inhibitor of protein kinase A (PKA) used extensively to investigate protein kinase-dependent cellular signal transduction pathways By antagonizing PKA activity H-9 dihydrochloride has been shown to attenuate cellular excitatory responses induced by serotonin (5-HT) and to directly influence physiological functions in the pharyngeal region Additionally in epithelial cell models H-9 dihydrochloride inhibits epidermal growth factor (EGF)-dependent signaling cascades suppressing cell proliferation This compound is widely used in cell biology research to dissect kinase-mediated regulatory mechanisms

Catalog No. 50-000-90041


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