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AdipoGen Heptelidic acid,Chemical. CAS: 57710-57-3

Supplier: AdipoGen AGCN20118M001

Heptelidic acid, AdipoGen Life Sciences. Chemical. CAS: 57710-57-3 (74310-84-2 deleted). Formula: C15H20O5. MW: 280.3. Isolated from Trichoderma sp. Antibiotic. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.
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