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Cayman Chemical HexylHIBOhydrobromIde 10mg
Supplier: Cayman Chemical 2916410 MG
An mGluR antagonist (Kbs = 140 and 110 µM for mGluR1α and mGluR5a, respectively); selective for group I mGluRs over mGluR2 (group II) and mGluR4a (group III) (Kbs = >1,000 µM for both), as well as AMPA, NMDA, and kainate receptors (IC50s = >100 µM for all); inhibits NMDA-induced seizures in mice at 6.3 and 12.5 mg/kg, i.c.v.; potentiates increases in plasma ACTH levels in a rat model of restraint stress
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