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Medchemexpress LLC Hjc0152 | 1420290-99-8 | MFCD29770804 | 99.8% | 406.65 g/mol | C15H14Cl3N3O4 | 10 MG
Supplier: Medchemexpress LLC HY10060210MG
HJC0152 is a small-molecule inhibitor of signal transducer and activator of transcription 3 (STAT3) for research use; it inhibits STAT3 signaling, decreases STAT3 promoter activity, reduces total STAT3, induces cleaved caspase-3, down-regulates cyclin D1, and shows antitumor activity in mouse xenograft models with no significant toxicity at tested doses.
- Inhibits STAT3 signaling and promoter activity in vitro.
- Reduces cell proliferation and induces apoptosis at low micromolar concentrations.
- Demonstrated tumor growth inhibition in mouse xenograft models without notable toxicity.
- High purity suitable for research applications (~99.8%).
- Available in small quantities for in vitro and in vivo studies.
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