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ABclonal Technology HMGA2 Rabbit mAb
Supplier: ABclonal Technology A24392100UL
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family HMG proteins function as architectural factors and are essential components of the enhancesome This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor Identification of the deletion amplification and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity Alternate transcriptional splice variants encoding different isoforms have been characterized
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