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Selleck Chemical LLC HS-10296 hydrochloride E4886-1G
Supplier: Selleck Chemical LLC E48861G
HS-10296 hydrochloride(Almonertinib (hydrochloride) HS-10296 HCl) is an irreversible third-generation inhibitor of EGFR tyrosine kinase that demonstrates high selectivity for EGFR-sensitizing mutations T790M resistance mutation It exhibits inhibitory activity against T790M T790M/L858R and T790M/Del19 with IC50 of 0 37 nM 0 29 nM and 0 21 nM respectively It also exhibits anti-tumor activity
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