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Creative Pegworks HS-PEG-SH, MW 10k - 5g
Supplier: Creative Pegworks PSB6095G
HS-PEG-SH is a linear homobifunctional PEG with two reactive free thiol. SH, sulfhydryl, or mercapto groups selectively react with maleimide and transition metal surface including gold, silver. HS-PEG-SH undergoes air oxidation and polymerization forming S-S disulfide bonds. Disulfide bond is reversible with reducing agents such as TECP. It is a useful reagent for reversible crosslinking PEGylation. HS-PEG-SH can crosslink two molecules containing maleimide. Thiol is very useful in thiol-ene reaction to react with acrylate, norbornene etc. Bifunctional thiol PEG is a common crosslinker in preparing hydrogels.
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