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Apexbio Technology LLC HU 211 112924-45-5 1mg
Supplier: Apexbio Technology LLC B53431
HU 211 is a small-molecule antagonist targeting N-methyl-D-aspartate (NMDA) receptors It is designed to inhibit NMDA receptor activity thereby modulating excitatory neurotransmission and associated neurotoxicity HU 211 exerts its biological activity primarily through non-competitive antagonism of NMDA receptors and competitively reduces the binding of [ 3H]MK-801 to neuronal membranes In in vitro studies HU 211 demonstrates dose-dependent inhibition of NMDA-induced neuronal toxicity and suppresses lipopolysaccharide (LPS)-triggered nitric oxide and tumor necrosis factor-alpha (TNF- ) release in macrophage cell lines Based on these pharmacological properties HU 211 holds research potential in studies of neurological injury and inflammation
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