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Sigma Aldrich Fine Chemicals Biosciences Human Fibroblast Like Syno
Supplier: Sigma Aldrich Fine Chemicals Biosciences 408OA05A

HFLS-RA provide an excellent cellular model for studying synoviocyte physiology in relation to development and treatment of rheumatoid arthritis. HFLS-RA have been used in numerous research studies to.nbspStudy signaling pathways implicated in the development of joint inflammation and rheumatoid arthritis (Abe, 2006 Akasaka, 2005 Bai, 2012 Fan, 2013 Furuhashi, 2008 Hashizume, 2008 Matsuyama, 2010 Tsuji, 1999 Yamaguch, 2012a,b Yano, 2001).nbspEvaluate possible contribution of EBV to nonresolving rheumatoid arthritis inflammation through inducing IL-6 production by synoviocytes (Chiu, 2013).nbspEvaluate the anti-inflammatory and antirheumatic activity of various compounds, such as celastrol (Venkatesha, 2011 Xu, 2013), triptolide (Kong, 2013 Lin, 2013), arsenic trioxide (Mei, 2011), Wen Luo Yin (Liu, 2013), bucillamine (Tsuji, 2007), therapeutic lyposomes (Harigai, 2007 Ichihara, 2011 Matsumoto, 2013 Negishi, 2011), anti-IL-6R and anti-CD319 antibodies (Suzuki, 2010 Woo, 2013), as well a
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