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BioVendor, LLC Mannose Receptor (CD206) Human, Mouse Monoclonal Antibody, Clone: MR 15-2-2 (100 ug)
Supplier: BioVendor, LLC QZBMR152100
Mannose Receptor (CD206) Human, Mouse Monoclonal Antibody, Clone: MR 15-2-2 (100 ug). Manufactured by QuickZyme Biosciences. Mouse MAb against native human mannose receptor purified from human placenta. Isotype IgG1. Formulation: in PBS containing 0.1% w/v BSA. Applications: Western blotting, flow cytometry, immunohistochemistry (IHC). Synonyms: Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, hMR. Summary: CD206 is an endocytic and phagocytic receptor that recognizes appropriately configured carbohydrate ligands in target molecules. CD206 is expressed mainly in mature tissue macrophages and immature dendritic cells, and may play a role in both innate and adaptive immune responses of the host. Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. The binding to mannose is calcium dependent.
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