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Proteintech Group Inc Human NGAL ELISA Kit 96well
Supplier: Proteintech Group Inc KE0014496T
Neutrophil gelatinase-associated lipocalin (NGAL) also known as Lipocalin-2 (LCN2), is a secreted glycoprotein that belongs to the lipocalin protein family. NGAL exists as a monomer, a homodimer and a disulfide-linked heterodimer in cells, covalently conjugated with gelatinase (matrix metalloproteinase-9, MMP-9) in order to decrease its degradation. Several roles of NGAL was identified, including iron trafficking, chemotactic, and promote cell differentiation and proliferation. NGAL was originally found in human neutrophils, and expressed in tissues containing renal, uterus, liver, spleen, as well as cardiomyocytes, neurons and immune cells. Studies showed that NGAL is a significant biomarker of cardiovascular diseases, ischemic stroke, acute renal injury, inflammation and metabolic diseases, and it can be detected in human serum, saliva and urine.
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