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Medchemexpress LLC HVH-2930 | 3034605-72-3 | 96.5% | 488.62 | 5 MG
Supplier: Medchemexpress LLC HY1617815MG
HVH-2930 is an inhibitor for heat shock protein 90 (HSP90). It inhibits the cell viability of BT474 (Trastuzumab sensitive) and JIMT-1 (Trastuzumab resistant) cells, with IC50 values of 6.86 μM and 4.42 μM, respectively. This inhibition is achieved through the downregulation of HSP90 client proteins. HVH-2930 has demonstrated antitumor efficacy in mouse models and possesses favorable pharmacokinetic characteristics in mice.
- Inhibits heat shock protein 90 (HSP90)
- Inhibits cell viability of BT474 and JIMT-1 cells
- Downregulates HSP90 client proteins
- Demonstrates antitumor efficacy in mouse models
- Possesses favorable pharmacokinetic characteristics in mice
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