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Medchemexpress LLC Hy-125880 | 1849603-72-0 | 99.7% | 450.55 g·mol⁻1 | C26H31FN4O2 | 25MG
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Supplier:  Medchemexpress LLC HY12588025MG

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SBI-553 is a small-molecule, brain-penetrant, β-arrestin-biased positive allosteric modulator of the neurotensin receptor 1 (NTR1), reported in the medicinal chemistry literature with an EC50 of about 0.34 μM. The compound is supplied for research use and is used in preclinical pharmacology and receptor signaling studies.

  • Potent NTR1 allosteric modulator with β-arrestin-biased activity.
  • Brain penetrant and reported to be orally bioavailable in preclinical studies.
  • Reported EC50 ≈ 0.34 μM for NTR1 modulation.
  • High chemical purity suitable for research use.
  • Available in multiple small pack sizes for laboratory use.
  • Chemical formula C26H31FN4O2; molecular weight 450.55 g·mol⁻1.

Catalog No. 50-002-35012


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