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Medchemexpress LLC Hydrastine | 118-08-1 | 99.6% | 1 MG
Supplier: Medchemexpress LLC HYB09271MG
Hydrastine, also known as (-)-β-Hydrastine, is a selective competitive inhibitor of tyrosine hydroxylase (TH) and the organic cation transporter OCT1. It inhibits dopamine biosynthesis and has been observed to cause neuronal toxicity through mitochondrial dysfunction. This compound is useful for research into Parkinson's disease-related dopaminergic neuronal damage.
- Selective competitive inhibitor of tyrosine hydroxylase (TH)
- Inhibits dopamine biosynthesis
- Inhibits organic cation transporter OCT1
- May cause neuronal toxicity via mitochondrial dysfunction
- Can exacerbate cell apoptosis when combined with L-DOPA
- Useful for studying Parkinson's disease-related neuronal damage
- Reduces PC12 cell viability in a concentration- and time-dependent manner
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