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Medchemexpress LLC Hydroquinidine | 1435-55-8 | 100.0% | 1 G
Supplier: Medchemexpress LLC HYB09971G
Hydroquinidine (Dihydroquinidine) is a potent ion channel blocker with strong anti-cancer activity across colon, pancreatic, and hepatocellular cancer cells. It is also known for its ability to prolong the QT interval and demonstrates antiarrhythmic efficacy.
- Potent ion channel blocker
- Exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
- Prolongs the QT interval
- Shows antiarrhythmic efficacy
- Demonstrates anti-clonogenic and anti-tumorigenic activities in pancreatic cancer cells
- Modulates gene expression, increasing CDKN1A, CDKN1B, and PUMA
- Reduces expression of BIRC5, AKT, MKI67, PCNA, and CCNE1 in various cancer cell lines
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