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Cayman Chemical HyocholIc AcId-d4 5mg

Supplier: Cayman Chemical 270335 MG

A naphthoquinone with diverse biological activities enantiomer of shikonin selectively inhibits tumor-specific PKM2 (IC50 0 3 M) over PKM1 and PKL inhibits proliferation of HCT116 and SW480 colorectal cancer cells (IC50s 2 38 and 4 53 M respectively) halts the cell cycle at the G1 phase and induces apoptosis in HCT116 cells at 3 M increases levels of Hsp70 in untreated and UVB-irradiated HaCaT cells as well as inhibits UVB-induced DNA fragmentation and caspase-3 activity in HaCaT cells at 1 M active against methicillin-sensitive and -resistant S aureus (MICs 6 25 g/ml) as well as vancomycin-sensitive and -resistant E faecalis (MICs 50 and 25 g/ml respectively) scavenges DPPH radicals in a cell-free assay (EC50 22 ppm)
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