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Medchemexpress LLC Idh-305 | 1628805-46-8 | MFCD31630851 | 99.2% | 490.45 g·mol⁻¹ | C23H22F4N6O2 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY104036100MG

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IDH-305 is an orally available, mutant-selective, brain-penetrant small-molecule inhibitor of isocitrate dehydrogenase 1 (IDH1) that targets oncogenic R132 mutations. It exhibits strong selectivity for mutant IDH1 isoforms and nanomolar potency against common variants, making it suitable for cellular and in vivo studies of IDH1-driven disease.

  • Mutant-selective IDH1 inhibition with nanomolar potency against common R132 variants.
  • Brain-penetrant compound suitable for central nervous system models.
  • High selectivity versus wild-type enzyme, supporting target-specific studies.
  • High purity suitable for research use.
  • Solubility and formulation data available for in vitro and in vivo applications.
  • Stable under recommended storage conditions for long-term use.

Catalog No. 50-002-43459


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