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Apexbio Technology LLC Idoxuridine 54-42-2 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B17735.1
Idoxuridine (5-Iodo-2 -deoxyuridine IdUrd) is a thymidine analog modified by iodine substitution primarily functioning as an inhibitor of viral DNA polymerase Its antiviral mechanism involves competitive incorporation into viral DNA during replication thereby disrupting DNA synthesis and inhibiting viral replication Experimental studies have confirmed inhibitory activity of Idoxuridine against herpes simplex virus (HSV) ocular infections Additionally evidence from in vitro assays indicates its inhibitory potential against feline herpesvirus and orthopoxvirus providing relevant tools for antiviral efficacy and infection-mechanism studies Reported IC50 values against HSV DNA polymerase typically range between 0 6 4 0 M thus establishing a quantitative basis for its antiviral applications in biomedical investigations
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