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Medchemexpress LLC IFNAR1 Human Bioti 50ug | 50ug

Supplier: Medchemexpress LLC HYP7814150UG
IFNAR1 one of the subunit of IFN- / receptor is a type I IFN receptor IFNAR1 forms the heterodimeric receptor with IFNAR2 IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2)[1][2] Upon activation by these IFNs IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events including the phosphorylation of Tyk2 and JAK1 STAT1 and STAT2[3] IFNAR1 Protein Human (Biotinylated HEK293 His-Avi) is a biotinylated recombinant human IFNAR1 (K28-K436) with C-terminal His and Avi tag which is produced in HEK293 cells
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