Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000375827

Medchemexpress LLC IHMT-MST1-58 | 2414484-25-4 | C21H22N6O3S | 1 ML
SDP

Supplier:  Medchemexpress LLC HY15125710MM/1ML

Encompass_Preferred

IHMT-MST1-58 is a potent, selective, mammalian, and orally active STE20-like protein 1 kinase (MST1) inhibitor with an IC50 value of 23 nM. It is utilized in research for type 1/2 diabetes.

  • Potent MST1 inhibitor with an IC50 of 23 nM.
  • Weak activity against MST2 and no activity against NEK3.
  • Strong binding affinity to MST1.
  • Inhibits phosphorylation of MST1 and downstream MOB1 autophosphorylation.
  • Provides protective effect for β cells against inflammatory cytokine damage.
  • Oral administration decreased fasting blood glucose and HbA1c levels in STZ-induced T1D/T2D mouse models.
  • Acceptable pharmacokinetic properties across species.
  • Purity: 99.05%.

Catalog No. 50-003-75827


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.