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Sigma Aldrich Fine Chemicals Biosciences IL 7 human Animal componen
Supplier: Sigma Aldrich Fine Chemicals Biosciences SRP326610UG
IL7 (interleukin 7) was first identified in 1988 in a bone marrow culture as a factor that facilitated murine B cell precursors growth. It is a cytokine produced by non-lymphoid cells in lymphoid organs. In humans it is also produced by keratinocytes peripheral blood dendritic cells follicular dendritic cells intestinal epithelial cells hepatic tissue endothelial cells smooth muscle cells and fibroblasts. IL7 gene is localized to human chromosome 8q12-q13. It is a glycoprotein with a four a-helix structure with a hydrophobic core. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.
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