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Medchemexpress LLC Imatinib-d3 hydrochloride | 1134803-18-1 | C29H28D3N7O | 1 MG
Supplier: Medchemexpress LLC HY15463S21MG
Imatinib-d3 hydrochloride is a deuterium labeled form of Imatinib, an orally bioavailable tyrosine kinase inhibitor. It selectively inhibits BCR/ABL, v-Abl, PDGFR, and c-kit kinase activity by binding near the ATP binding site. The compound also inhibits SARS-CoV and MERS-CoV.
- Used as a tracer for quantitation during drug development
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Selectively inhibits BCR/ABL, v-Abl, PDGFR, and c-kit kinase activity
- Inhibits SARS-CoV and MERS-CoV
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs
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