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Medchemexpress LLC INCB059872 dihydrochloride | 3062683-32-0 | 99.6% | C23H36Cl2N2O3 | 1 MG
Supplier: Medchemexpress LLC HY141677A1MG
INCB059872 dihydrochloride is a potent, orally active, selective, and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor, primarily used for research related to myeloid leukemia. In vitro studies show that it increases enhancer activity and gene expression in 293T cells, and causes growth defects in THP-1 cells. Additionally, it regulates PRO-seq analysis and in vivo studies indicate changes in bone marrow progenitor populations in mice.
- Potent, orally active, selective, and irreversible LSD1 inhibitor.
- Used for research related to myeloid leukemia.
- Increases enhancer activity and gene expression in 293T cells.
- Causes growth defect in THP-1 cells.
- Regulates PRO-seq analysis for identifying genes and enhancers.
- Leads to changes in bone marrow progenitor populations in C57BL/6J mice.
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