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Abcam Iodoacetamide, Alkylating agent, 25G
Supplier: Abcam AB14621225G
MW 184.96 g/mol, Purity >98%. Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
The product is subject to the following: Abcam Restricted Use Statement
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