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Cayman Chemical IodophenpropIthydrobromID 10mg

Supplier: Cayman Chemical 3285010 MG
A histamine H3 receptor antagonist (pA2 = 9.6); increases forskolin-induced cAMP production in SK-N-MC cells expressing the recombinant human H3 receptor (EC50 = 25.1 nM); an inhibitor of NR1/NR2A, NR1/NR2B, NR1/NR2C, and NR1/NR2D subunit-containing NMDA receptors (IC50s = 1.3, 1.4, 9.7, and 14 µM, respectively, for the rat recombinant receptors); induces scratching behavior in mice at 10 nmol intradermally and reduces amygdala-kindled seizure duration in rats (ED50 = 2.54 mg/kg)
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