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Medchemexpress LLC Irak4-in-14 | 2667681-71-0 | 99.0% | 489.55 g/mol | C25H28FN9O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1461125MG

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IRAK4-IN-14 is a small-molecule, selective, orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) characterized for biochemical potency and in vivo pharmacokinetics. It has been profiled for cellular activity and shows favorable oral exposure in preclinical species.

  • Potent IRAK4 inhibition (IC50 0.003 μM).
  • Cell pIRAK4 activity (IC50 0.11 μM).
  • Selective kinase profile with limited off-target activity reported.
  • Oral bioavailability approximately 66% in mouse.
  • Molecular formula C25H28FN9O; molecular weight 489.55 g/mol.
  • Reported purity 99.01%.
  • Available as solid packages (including 5 mg) and as a 10 mM solution in DMSO.

Catalog No. 50-002-22837


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