Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Irak4-in-21 | 2170694-04-7 | C28H28FN7O2 | 1 MG
Supplier: Medchemexpress LLC HY1513631MG
IRAK4-IN-21 (compound 17) is an orally active, potent, and selective IRAK4 inhibitor. It effectively inhibits IL-23 production and can be used in studies of autoimmune diseases such as plaque psoriasis and psoriatic arthritis.
- Potent and selective IRAK4 inhibitor with IC50 values of 5 nM for IRAK4 and 56 nM for TAK1.
- Effectively inhibits IL-23 production (IC50 = 0.17 μM).
- Decreases levels of IL-23, IL-6, and MIP-1β in various cell lines.
- Shows moderate efficacy in acute animal model studies for inhibition of IL-6 production.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?