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Cayman Chemical IRL 1620 trifluoroacetate sa
Supplier: Cayman Chemical 30980500 UG
A peptide ETB receptor agonist; selectively binds to ETB receptors (Ki = 16 pM) over ETA receptors (IC50 = 1.9 µM); induces contractions of isolated guinea pig trachea from 0.01-1 µM; reduces MAP in normotensive rats and SHRs and diminishes the transient depressor response in SHRs at 1 nmol/kg; reduces infarct volume and improves motor and neurological function in a rat model of cerebral ischemia; improves Aβ-induced spatial memory deficits in a rat model of Alzheimer's disease
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