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Cayman Chemical IsogInkgetIn 10mg

Supplier: Cayman Chemical 2510410 MG
A biflavonoid inhibitor of pre-mRNA splicing; reduces the activity of an mRNA-dependent luciferase reporter, shifts the total RNA extract from predominantly mRNA to pre-mRNA, and arrests cell growth in HEK293 cells at 33 μM; suppresses Con A- and LPS-induced mouse lymphocyte proliferation at 10 μM; suppresses PMA- and A23187-induced arachidonic acid release in rat peritoneal macrophages at 10 μM; dose-dependently reduces MMP-9 activity, expression, and mRNA levels in and decreases cell invasion by HT1080 fibrosarcoma cells from 5-20 μM
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