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Medchemexpress LLC Istradefylline | 155270-99-8 | 99.9% | 384.43 | 25 MG
Supplier: Medchemexpress LLC 25MGHY10888
Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist, primarily investigated in experimental models of Parkinson's disease. It is intended for research use only.
- Very potent and selective adenosine A2A receptor antagonist.
- Orally active compound.
- Attenuates dopamine and DOPAC depletions in Parkinson's disease models.
- Reverses drug-induced catalepsy and hypokinesia.
- Increases locomotor activity and improves motor disability in MPTP-treated marmosets.
- Shows potentially additive effects with L-DOPA on locomotor activity without increasing dyskinesia.
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