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Selleck Chemical LLC Isuzinaxib S0777-25MG
Supplier: Selleck Chemical LLC S077725MG
Isuzinaxib (APX-115 free base Ewha-18278 free base) is a potent orally active inhibitor of pan NADPH oxidase (pan-Nox) with Ki of 1 08 M 0 57 M and 0 63 M for Nox1 Nox2 and Nox4 respectively APX-115 free base (Ewha-18278 free base) significantly suppresses the expression of inflammatory molecules including MCP-1/CCL2 IL-6 and TNF in the diabetic kidney
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