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Medchemexpress LLC Itacitinib (INCB039110) | 1334298-90-6 | 99.97% | 553.51 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY169971MG

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Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1, exhibiting an IC50 of 2 nM for human JAK1. It demonstrates over 20-fold selectivity for JAK1 compared to JAK2, and over 100-fold selectivity over JAK3 and TYK2. Itacitinib is currently utilized in research concerning myelofibrosis.

  • Orally active and selective JAK1 inhibitor.
  • IC50 of 2 nM for human JAK1.
  • High selectivity: >20-fold over JAK2, and >100-fold over JAK3 and TYK2.
  • Used in myelofibrosis research.

Catalog No. 50-003-91327


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