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Medchemexpress LLC Ivacaftor-d19 (VX-770-d19) | 1413431-22-7 | 98.1% | 1 MG

Supplier: Medchemexpress LLC HY13017S11MG
Ivacaftor-d19 is a potent CFTR modulator with an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. It functions as an orally active and enhanced deuterated Ivacaftor analog for cystic fibrosis research. Deuterated compounds offer potential advantages such as extending in vivo half-life, improving oral bioavailability, enhancing metabolic characteristics, improving drug safety, and preserving therapeutic properties.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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