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Medchemexpress LLC IW927 | 389142-48-7 | 99.2% | 441.57 | C22H23N3O3S2 | 50 MG
Supplier: Medchemexpress LLC HY11892250MG
IW927 is a photochemically activated small-molecule inhibitor of the TNF-α-TNFR1 interaction for in vitro research. It exhibits light-dependent behavior, forming reversible binding in dark conditions and irreversible covalent modification of TNFRc1 under light; shows a binding IC50 of approximately 50 nM and disrupts TNFα-induced IκB phosphorylation (IC50 ≈ 600 nM).
- Photochemically activated TNF-α-TNFR1 interaction inhibitor.
- Exhibits light-dependent covalent binding to TNFRc1.
- Binding IC50 approximately 50 nM, useful for biochemical assays.
- Disrupts TNFα-induced IκB phosphorylation (IC50 ≈ 600 nM).
- Supplied as a powder with cold storage recommendations for stability.
- Intended for in vitro signaling and apoptosis research.
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