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Medchemexpress LLC Izuforant | 1429374-83-3 | C12H12BrN7 | 10MG
Supplier: Medchemexpress LLC HY14727610MG
Izuforant is a small-molecule research compound that acts as a selective histamine H4 receptor antagonist. It is orally active and has demonstrated potent activity versus human H4R (IC50 = 36 nM), with reported anti-pruritic and anti-inflammatory effects; the compound also shows weaker binding to the 5-HT3 receptor (IC50 ≈ 9.1 μM). Izuforant is provided as a research standard for laboratory and preclinical studies.
- Potent H4R antagonist activity (IC50 = 36 nM).
- Demonstrates anti-pruritic and anti-inflammatory effects.
- Orally active small-molecule suitable for in vivo studies.
- Secondary 5-HT3 receptor binding at micromolar potency.
- Molecular formula C12H12BrN7; molecular weight 334.17.
- Supplied as a high-purity research standard for laboratory use.
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