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Medchemexpress LLC JAB-3068 hydrochloride (synonyms: SHP2-IN-6 hydrochloride) | 2169223-49-6 | 98.9% | 1 ML
Supplier: Medchemexpress LLC HY131132A10MM/1ML
JAB-3068 hydrochloride (SHP2-IN-6) is a potent SHP2 inhibitor with an IC50 of 25.8 nM. It inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM in vitro. This compound is derived from patent WO2017211303A1, compound 7.
- Potent SHP2 inhibitor with an IC50 of 25.8 nM.
- Inhibits KYSE-520 cell proliferation with an IC50 of 2.17 μM.
- Molecular weight: 513.00.
- Chemical formula: C22H27ClF2N6O2S.
- Appears as a light yellow to yellow solid.
- Solubility in DMSO is 115 mg/mL (224.17 mM).
- For in solvent storage: -80°C for 6 months or -20°C for 1 month.
- Store at -20°C in sealed conditions, away from moisture and light.
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