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Cayman Chemical JBSNF-000088 250mg
Supplier: Cayman Chemical 29920250 MG
An inhibitor of NMMT (IC50s = 1.8, 2.8, and 5 µM for human, monkey, and mouse NNMT, respectively); inhibits NNMT and reduces MNA levels in U2OS and 3T3L1 cells (IC50s = 1.6 and 6.3 µM, respectively); reduces visceral WAT, MNA levels, body weight, fed blood glucose levels, and plasma and liver triglyceride levels, and improves oral glucose tolerance in a mouse model of DIO; also improves glucose tolerance, without affecting body weight, in the ob/ob and db/db mouse models of insulin resistance and diabetes, respectively
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