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TARGETMOL CHEMICALS INC JGB1741 5MG
Supplier: TARGETMOL CHEMICALS INC T220945MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JGB1741 (ILS-JGB-1741) is a potent and selective inhibitor of SIRT1 with an IC50 of 15 uM. JGB1741 modulates Bax/Bcl2 ratio cytochrome c release and PARP cleavage and increases the acetylated p53 levels leading to p53-mediated apoptosis. JGB1741 can be used in studies about breast cancer. purity: 97%
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