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Medchemexpress LLC JH295 25mg | 1311143-71-1 | 320.35 g/mol | C18H16N4O2 | 25 MG

Supplier: Medchemexpress LLC HY11642325MG
This compound (CAS 1311143-71-1) is a small-molecule, cysteine-targeted inhibitor of NIMA-related kinase 2 (Nek2) that irreversibly inactivates the enzyme via alkylation of a catalytic cysteine. It is supplied as a solid for research use; solutions should be prepared fresh due to limited stability in solution.
- Potent, irreversible Nek2 inhibition with reported IC50 ≈ 770 nM.
- Molecular formula C18H16N4O2; molecular weight 320.35 g/mol.
- High purity (98.66%) and yellow to orange solid appearance.
- Soluble in DMSO (~55 mg/mL); sonication and newly opened DMSO recommended.
- Store at -20°C under inert atmosphere; avoid extended storage in solution.
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