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Medchemexpress LLC JI-101 | 900573-88-8 | 99.0% | 466.33 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY162655MG

Encompass_Preferred

JI-101 is an orally available multi-kinase inhibitor of VEGFR2, PDGFRβ, and EphB4 with potent anti-cancer activity. It is for research use only and is not sold to patients.

  • Orally available multi-kinase inhibitor.
  • Inhibits VEGFR2, PDGFRβ, and EphB4.
  • Potent anti-cancer activity.
  • Stable in all preclinical and human liver microsomes.
  • Rapidly absorbed after oral administration, reaching Cmax within 2 hours.
  • Extensive tissue distribution with rapid and preferred uptake into lung tissue.
  • Oral bioavailability is 55%.
  • Primary route of elimination is feces.

Catalog No. 50-003-91856


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