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Apexbio Technology LLC JNJ-10229570 524923-88-4 1mL(10 mM in DMSO)
Supplier: Apexbio Technology LLC BA55405.1
JNJ-10229570 (CAS 524923-88-4) is a selective antagonist of melanocortin receptors MC1R and MC5R It inhibits ligand binding to MC1R and MC5R in human cells with reported inhibition values of 270 nM and 200 nM respectively Through antagonism of these receptors JNJ-10229570 suppresses sebocyte differentiation and the biosynthesis of cortex-specific lipids This compound serves as a valuable tool for investigating the roles of melanocortin signaling in lipid metabolism and sebaceous gland physiology
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