Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000238094

Medchemexpress LLC JNJ-42253432 | 1428327-35-8 | MFCD34676648 | 98.2% | 446.63 g·mol⁻¹ | C28H38N4O | 10MG
SDP

Supplier:  Medchemexpress LLC HY12348110MG

Encompass_Preferred

JNJ-42253432 is a CNS-penetrant, high-affinity, orally active antagonist of the P2X7 receptor used in preclinical pharmacology to probe P2X7-mediated signaling and receptor occupancy in the central nervous system.

  • CNS-penetrant P2X7 receptor antagonist
  • High affinity: rat pKi 9.1, human pKi 7.9
  • Oral activity demonstrated in preclinical models
  • Soluble in DMSO (reported 100 mg/mL) and usable in in-vivo co-solvent formulations
  • Reported purity 98.15%
  • Molecular weight 446.63 g·mol⁻¹; formula C28H38N4O
  • Storage recommendations: powder -20°C long term; in solution -80°C recommended

Catalog No. 50-002-38094


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.