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Medchemexpress LLC Jnj28871063 hydrochloride | 944342-90-9 | 98.4% | 519.42 | C24H28Cl2N6O3 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY103441100MG

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JNJ28871063 hydrochloride is an ATP-competitive pan-ErbB (EGFR/ErbB) kinase inhibitor used for research. It is orally active, shows potent inhibition of ErbB family kinases, crosses the blood-brain barrier, and has demonstrated antitumor activity in xenograft models.

  • Orally active, ATP-competitive pan-ErbB kinase inhibitor.
  • Potent inhibition of EGFR (ErbB1), ErbB2, and ErbB4 (IC50 ≈ 21-38 nM).
  • Crosses the blood-brain barrier.
  • Demonstrated antitumor activity in EGFR/ErbB2-overexpressing xenograft models.
  • Supplied as the hydrochloride salt.
  • Intended for in vitro and in vivo research use only.

Catalog No. 50-002-46784


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