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Cayman Chemical (+)-JQ1, 1268524-70-4, 5 mg

Supplier: Cayman Chemical 111875
Molecular Formula C23H25ClN4O2S, Purity ≥98%, Formula Weight 457.0, Synonym: (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 1,1-dimethylethyl ester; Displaces BET proteins from chromatin by competitively binding to the acetyl-lysine recognition pocket of BET bromodomains; binds BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively.
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