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Apexbio Technology LLC JTC-801 244218-51-7 5mg
Supplier: Apexbio Technology LLC A84565
JTC-801 (CAS 244218-51-7) is a potent and selective antagonist of the nociceptin/orphanin FQ peptide (NOP also known as KOR-3) receptor exhibiting a Ki value of 8 2 nM Compared to its activity at the NOP receptor JTC-801 demonstrates markedly lower affinity for the human - - and -opioid receptors with selectivity ratios of approximately 12 5- 129- and 1055-fold respectively This compound is utilized in research to investigate the physiological and pharmacological roles of NOP receptor signaling including its involvement in pain modulation and potential therapeutic approaches targeting the nociceptin system
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