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Selleck Chemical LLC JTE-607 Dihydrochloride
Supplier: Selleck Chemical LLC E03145MG
JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis JTE-607 is a multiple cytokine production inhibitor that targets CPSF3 and inhibits pre-mRNA processing JTE-607 inhibits tumor necrosis factor (TNF)-alpha interleukin (IL)-1beta IL-6 IL-8 and IL-10 from LPS-stimulated human PBMCs with IC50 values of 11 nM 5 9 nM 8 8 nM 7 3 nM and 9 1 nM respectively
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