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Medchemexpress LLC K-756 | 130017-40-2 | 433.50 | 100 MG
Supplier: Medchemexpress LLC HYU00422100MG
K-756 is a direct and selective tankyrase (TNKS) inhibitor that inhibits the ADP-ribosylation activity of TNKS1 and TNKS2. This novel and selective Wnt/β-catenin pathway inhibitor binds to the induced pocket of TNKS, inhibiting its enzyme activity and showing isoform selectivity.
- Direct and selective tankyrase (TNKS) inhibitor
- Inhibits ADP-ribosylation activity of TNKS1 and TNKS2
- Novel and selective Wnt/β-catenin pathway inhibitor
- Binds to the induced pocket of TNKS
- Inhibits cell growth in APC-mutant colorectal cancer cells
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