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Apexbio Technology LLC K03861 853299-07-7 5mg
Supplier: Apexbio Technology LLC B60425
K03861 (CAS 853299-07-7) is a small molecule inhibitor targeting cyclin-dependent kinase 2 (CDK2) Acting as a type II inhibitor of CDK2 K03861 interacts with regions beyond the ATP binding pocket and can antagonize cyclin binding X-ray crystallography studies have demonstrated that K03861 establishes a distinctive binding conformation with CDK2 distinct from type I inhibitors Given the central role of CDK2 in cell cycle regulation proliferation and transcription K03861 provides a valuable chemical tool for investigating the structure function and inhibition of cyclin CDK2 complexes in cellular proliferation and cancer research
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