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Apexbio Technology LLC Kaempferide 491-54-3 5mg
Supplier: Apexbio Technology LLC A35225
Kaempferide (CAS 491-54-3) is a plant-derived O-methylflavone studied for phytochemical-mediated regulation of estrogen receptor (ER ) It is designed to modulate ER signaling pathways thereby affecting estrogen-related cellular processes Kaempferide exerts its biological activity primarily by inhibiting the proliferation of ER -overexpressing colon carcinoma cells through a ligand-independent mechanism and inducing G0/G1 cell cycle arrest while elevating antioxidant enzyme activities In in vitro studies kaempferide demonstrates inhibitory activity in ER -overexpressing colon carcinoma cell lines such as HCT8 IC50 values have not yet been clearly established Based on these pharmacological properties kaempferide holds research potential in colorectal cancer prevention and ER -associated pathway modulation
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