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ABclonal Technology KD Validated IL13 Rabbit mAb
SDP

Supplier:  ABclonal Technology A2341520UL

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This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells This cytokine is involved in several stages of B-cell maturation and differentiation It up-regulates CD23 and MHC class II expression and promotes IgE isotype switching of B cells This cytokine down-regulates macrophage activity thereby inhibits the production of pro-inflammatory cytokines and chemokines This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils This gene IL3 IL5 IL4 and CSF2 form a cytokine gene cluster on chromosome 5q with this gene particularly close to IL4

Catalog No. 50-000-06709


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